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ASPP2 involvement in p53-mediated HIV-1 envelope glycoprotein gp120 neurotoxicity in mice cerebrocortical neurons

The mechanisms behind HIV-1-associated neurocognitive disorders are still unclear. Apoptosis-stimulating protein 2 of p53 (ASPP2) is a damage-inducible p53-binding protein that stimulates p53-mediated apoptosis and transactivates proapoptotic and cell cycle regulatory genes. It has been reported tha...

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Detalles Bibliográficos
Autores principales:	Liu, Zhiying, Zang, Yunjin, Qiao, Luxin, Liu, Kai, Ouyang, Yabo, Zhang, Yulin, Chen, Dexi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022057/ https://www.ncbi.nlm.nih.gov/pubmed/27625111 http://dx.doi.org/10.1038/srep33378

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