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Elevation of Il6 is associated with disturbed let-7 biogenesis in a genetic model of depression

Elevation of the proinflammatory cytokine IL-6 has been implicated in depression; however, the mechanisms remain elusive. MicroRNAs (miRNAs) are small non-coding RNAs that inhibit gene expression post-transcriptionally. The lethal-7 (let-7) miRNA family was suggested to be involved in the inflammati...

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Detalles Bibliográficos
Autores principales:	Wei, Y B, Liu, J J, Villaescusa, J C, Åberg, E, Brené, S, Wegener, G, Mathé, A A, Lavebratt, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022082/ https://www.ncbi.nlm.nih.gov/pubmed/27529677 http://dx.doi.org/10.1038/tp.2016.136

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