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Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report

BACKGROUND: Desmoid tumors, which are associated with familial adenomatous polyposis (FAP), tend to occur frequently in the abdominal wall and mesentery. Currently, there are no recognized treatments other than surgery, and frequent surgeries result in gastrointestinal obstructions and functional ga...

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Autores principales: Nagata, Takuya, Demizu, Yusuke, Okumura, Tomoyuki, Sekine, Shinichi, Hashimoto, Naoki, Fuwa, Nobukazu, Okimoto, Tomoaki, Shimada, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022152/
https://www.ncbi.nlm.nih.gov/pubmed/27624694
http://dx.doi.org/10.1186/s12957-016-1000-8
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author Nagata, Takuya
Demizu, Yusuke
Okumura, Tomoyuki
Sekine, Shinichi
Hashimoto, Naoki
Fuwa, Nobukazu
Okimoto, Tomoaki
Shimada, Yutaka
author_facet Nagata, Takuya
Demizu, Yusuke
Okumura, Tomoyuki
Sekine, Shinichi
Hashimoto, Naoki
Fuwa, Nobukazu
Okimoto, Tomoaki
Shimada, Yutaka
author_sort Nagata, Takuya
collection PubMed
description BACKGROUND: Desmoid tumors, which are associated with familial adenomatous polyposis (FAP), tend to occur frequently in the abdominal wall and mesentery. Currently, there are no recognized treatments other than surgery, and frequent surgeries result in gastrointestinal obstructions and functional gastrointestinal disorders. CASE PRESENTATION: After surgery that was performed on a 39-year-old patient with FAP, we performed a second tumor excision which was the procedure used for frequently occurring mesenteric desmoid tumors. It was determined that the enlarged tumor would be difficult to operate on through an abdominal incision. Subsequently, the carbon ion radiotherapy of 50 Gy was then performed on the patient. Three years later, the tumor still remains reduced in size. In addition, we have not observed any negative effect on the digestive tract. CONCLUSIONS: This is the first instance that the carbon ion radiotherapy has been effective for the unresected desmoid tumor, and it is believed that this will become the one effective option for the treatment of desmoid tumors.
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spelling pubmed-50221522016-09-20 Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report Nagata, Takuya Demizu, Yusuke Okumura, Tomoyuki Sekine, Shinichi Hashimoto, Naoki Fuwa, Nobukazu Okimoto, Tomoaki Shimada, Yutaka World J Surg Oncol Case Report BACKGROUND: Desmoid tumors, which are associated with familial adenomatous polyposis (FAP), tend to occur frequently in the abdominal wall and mesentery. Currently, there are no recognized treatments other than surgery, and frequent surgeries result in gastrointestinal obstructions and functional gastrointestinal disorders. CASE PRESENTATION: After surgery that was performed on a 39-year-old patient with FAP, we performed a second tumor excision which was the procedure used for frequently occurring mesenteric desmoid tumors. It was determined that the enlarged tumor would be difficult to operate on through an abdominal incision. Subsequently, the carbon ion radiotherapy of 50 Gy was then performed on the patient. Three years later, the tumor still remains reduced in size. In addition, we have not observed any negative effect on the digestive tract. CONCLUSIONS: This is the first instance that the carbon ion radiotherapy has been effective for the unresected desmoid tumor, and it is believed that this will become the one effective option for the treatment of desmoid tumors. BioMed Central 2016-09-13 /pmc/articles/PMC5022152/ /pubmed/27624694 http://dx.doi.org/10.1186/s12957-016-1000-8 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Nagata, Takuya
Demizu, Yusuke
Okumura, Tomoyuki
Sekine, Shinichi
Hashimoto, Naoki
Fuwa, Nobukazu
Okimoto, Tomoaki
Shimada, Yutaka
Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
title Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
title_full Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
title_fullStr Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
title_full_unstemmed Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
title_short Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
title_sort carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022152/
https://www.ncbi.nlm.nih.gov/pubmed/27624694
http://dx.doi.org/10.1186/s12957-016-1000-8
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