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Pim2 is important for regulating DNA damage response in multiple myeloma cells

Pan proviral integrations of Moloney virus (PIM) inhibition in multiple myeloma (MM) results in reduced cell viability in tested human-derived MM cell lines and reduces tumor burden in xenograft mouse models, making PIMs important therapeutic targets for the disease. PIM kinase inhibitors are curren...

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Detalles Bibliográficos
Autores principales: Ramachandran, J, Santo, L, Siu, K T, Panaroni, C, Raje, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022183/
https://www.ncbi.nlm.nih.gov/pubmed/27564460
http://dx.doi.org/10.1038/bcj.2016.73