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Pim2 is important for regulating DNA damage response in multiple myeloma cells
Pan proviral integrations of Moloney virus (PIM) inhibition in multiple myeloma (MM) results in reduced cell viability in tested human-derived MM cell lines and reduces tumor burden in xenograft mouse models, making PIMs important therapeutic targets for the disease. PIM kinase inhibitors are curren...
Autores principales: | Ramachandran, J, Santo, L, Siu, K T, Panaroni, C, Raje, N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022183/ https://www.ncbi.nlm.nih.gov/pubmed/27564460 http://dx.doi.org/10.1038/bcj.2016.73 |
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