A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

BACKGROUND: Ferroquine (SSR97193) is a candidate anti-malarial currently undergoing clinical trials for malaria. To better understand its pharmacokinetic (PK) and pharmacodynamic (PD) parameters the compound was tested in the experimentally induced blood stage malaria infection model in volunteers....

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Detalles Bibliográficos
Autores principales: McCarthy, James S., Rückle, Thomas, Djeriou, Elhadj, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O’Rourke, Peter, Griffin, Paul, Marquart, Louise, Hooft van Huijsduijnen, Rob, Möhrle, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022189/
https://www.ncbi.nlm.nih.gov/pubmed/27624471
http://dx.doi.org/10.1186/s12936-016-1511-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022189/
https://www.ncbi.nlm.nih.gov/pubmed/27624471
http://dx.doi.org/10.1186/s12936-016-1511-3

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