Cargando…

A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells

BACKGROUND: Mesenchymal stem cells (MSCs) have prospective applications in regenerative medicine and tissue engineering but to what extent phenotype and differentiation capacity alter with ageing is uncertain. Consequently, any loss in functionality with age would have profound consequences for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peffers, Mandy J., Collins, John, Loughlin, John, Proctor, Carole, Clegg, Peter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022190/ https://www.ncbi.nlm.nih.gov/pubmed/27624072 http://dx.doi.org/10.1186/s13287-016-0384-2

Ejemplares similares

Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq
por: Peffers, Mandy Jayne, et al.
Publicado: (2016)

Radiation-Induced Alterations of Osteogenic and Chondrogenic Differentiation of Human Mesenchymal Stem Cells
por: Cruet-Hennequart, Séverine, et al.
Publicado: (2015)

Editorial: The Epigenetics in Osteogenic and Chondrogenic Differentiation of Mesenchymal Stem Cells
por: Della Bella, Elena, et al.
Publicado: (2021)

Epigenetic Regulation of Osteogenic and Chondrogenic Differentiation of Mesenchymal Stem Cells in Culture
por: Eslaminejad, Mohamadreza Baghaban, et al.
Publicado: (2013)

The role of mitochondria in osteogenic, adipogenic and chondrogenic differentiation of mesenchymal stem cells
por: Li, Qianqian, et al.
Publicado: (2017)

Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells
por: Zhou, Jia-Qi, et al.
Publicado: (2023)

The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies
por: Iaquinta, Maria Rosa, et al.
Publicado: (2021)

The role of Trithorax family regulating osteogenic and Chondrogenic differentiation in mesenchymal stem cells
por: Ma, Qingge, et al.
Publicado: (2022)

Dielectrophoretic Characterization of Tenogenically Differentiating Mesenchymal Stem Cells
por: Giduthuri, Anthony T., et al.
Publicado: (2021)

Systems approaches in osteoarthritis: Identifying routes to novel diagnostic and therapeutic strategies
por: Mueller, Alan J., et al.
Publicado: (2017)

Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation
por: Peffers, Mandy J., et al.
Publicado: (2014)

Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females
por: Pease, Louise I., et al.
Publicado: (2017)

Donor age affects proteome composition of tenocyte-derived engineered tendon
por: Turlo, Agnieszka J., et al.
Publicado: (2018)

Degenerative tendon matrix induces tenogenic differentiation of mesenchymal stem cells
por: Hwang, Joongwon, et al.
Publicado: (2023)

Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells
por: Li, Chenghai, et al.
Publicado: (2018)

Adipose-derived mesenchymal stem cells with hypoxic preconditioning improve tenogenic differentiation
por: Guo, Xing, et al.
Publicado: (2022)

Effects of Antithrombotic Drugs Fondaparinux and Tinzaparin on In Vitro Proliferation and Osteogenic and Chondrogenic Differentiation of Bone-Derived Mesenchymal Stem Cells
por: Papathanasopoulos, Argiris, et al.
Publicado: (2011)

Transcriptomic signatures in cartilage ageing
por: Peffers, Mandy Jayne, et al.
Publicado: (2013)

Transcriptomic profiling of cartilage ageing
por: Peffers, Mandy Jayne, et al.
Publicado: (2014)

Mesenchymal stem cells derived from human induced pluripotent stem cells retain adequate osteogenicity and chondrogenicity but less adipogenicity
por: Kang, Ran, et al.
Publicado: (2015)

Different tenogenic differentiation capacities of different mesenchymal stem cells in the presence of BMP-12
por: Dai, Linghui, et al.
Publicado: (2015)

BMP14 induces tenogenic differentiation of bone marrow mesenchymal stem cells in vitro
por: Wang, Dan, et al.
Publicado: (2018)

Cartilage Oligomeric Matrix Protein Gene Multilayers Inhibit Osteogenic Differentiation and Promote Chondrogenic Differentiation of Mesenchymal Stem Cells
por: Guo, Peng, et al.
Publicado: (2014)

Two-photon FLIM of NAD(P)H and FAD in mesenchymal stem cells undergoing either osteogenic or chondrogenic differentiation
por: Meleshina, Aleksandra V., et al.
Publicado: (2017)

Comparison of Osteogenic and Chondrogenic Differentiation Ability of Buccal Fat Pad Derived Mesenchymal Stem Cells and Gingival Derived Cells
por: Ghaderi, Hamid, et al.
Publicado: (2018)

Abnormal osteogenic and chondrogenic differentiation of human mesenchymal stem cells from patients with adolescent idiopathic scoliosis in response to melatonin
por: Chen, Chong, et al.
Publicado: (2016)

Tenogenic Properties of Mesenchymal Progenitor Cells Are Compromised in an Inflammatory Environment
por: Brandt, Luisa, et al.
Publicado: (2018)

Osteogenic and Chondrogenic Potential of Periosteum-Derived Mesenchymal Stromal Cells: Do They Hold the Key to the Future?
por: Jeyaraman, Madhan, et al.
Publicado: (2021)

Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells
por: Theodossiou, Sophia K., et al.
Publicado: (2021)

Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells
por: Sheng, Renwang, et al.
Publicado: (2023)

Osteogenic and Chondrogenic Potential of the Supramolecular Aggregate T-LysYal®
por: Di Benedetto, Adriana, et al.
Publicado: (2020)

Ex Vivo Equine Cartilage Explant Osteoarthritis Model: A Metabolomics and Proteomics Study
por: Anderson, James R., et al.
Publicado: (2020)

The Spatiotemporal Role of COX-2 in Osteogenic and Chondrogenic Differentiation of Periosteum-Derived Mesenchymal Progenitors in Fracture Repair
por: Huang, Chunlan, et al.
Publicado: (2014)

Nanotextured silk fibroin/hydroxyapatite biomimetic bilayer tough structure regulated osteogenic/chondrogenic differentiation of mesenchymal stem cells for osteochondral repair
por: Shang, Lingling, et al.
Publicado: (2020)

Tenogenically Induced Allogeneic Mesenchymal Stem Cells for the Treatment of Proximal Suspensory Ligament Desmitis in a Horse
por: Vandenberghe, Aurélie, et al.
Publicado: (2015)

Influence of mechanical and TGF-β3 stimulation on the tenogenic differentiation of tonsil-derived mesenchymal stem cells
por: Wee, Jaeyeon, et al.
Publicado: (2022)

Proliferation and tenogenic differentiation of bone marrow mesenchymal stem cells in a porous collagen sponge scaffold
por: Zhang, Bing-Yu, et al.
Publicado: (2021)

Proteomics reveals multiple routes to the osteogenic phenotype in mesenchymal stem cells
por: Bennett, Kristin P, et al.
Publicado: (2007)

The Osteogenic and Tenogenic Differentiation Potential of C3H10T1/2 (Mesenchymal Stem Cell Model) Cultured on PCL/PLA Electrospun Scaffolds in the Absence of Specific Differentiation Medium
por: Baudequin, Timothée, et al.
Publicado: (2017)

Donor age effects on in vitro chondrogenic and osteogenic differentiation performance of equine bone marrow- and adipose tissue-derived mesenchymal stromal cells
por: Bagge, Jasmin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1taq2mvbomt1ge7gs82kgif43i