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Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake

BACKGROUND: Snakebites cause considerable morbidity and mortality in tropical and subtropical countries even though existing treatment methods can prevent most deaths if presentation occurs early to hospitals. Envenomation by unidentified snakes is common in central Sri Lanka. Management of such pat...

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Autores principales: Ehelepola, N. D. B., Samaranayake, S. M. A. N., Basnayake, B. M. L. S., Amiyangoda, C. G. K., Dhanapala, D. M. U. C. B., Kalupahana, K. L. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022210/
https://www.ncbi.nlm.nih.gov/pubmed/27651731
http://dx.doi.org/10.1186/s41182-016-0029-2
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author Ehelepola, N. D. B.
Samaranayake, S. M. A. N.
Basnayake, B. M. L. S.
Amiyangoda, C. G. K.
Dhanapala, D. M. U. C. B.
Kalupahana, K. L. R.
author_facet Ehelepola, N. D. B.
Samaranayake, S. M. A. N.
Basnayake, B. M. L. S.
Amiyangoda, C. G. K.
Dhanapala, D. M. U. C. B.
Kalupahana, K. L. R.
author_sort Ehelepola, N. D. B.
collection PubMed
description BACKGROUND: Snakebites cause considerable morbidity and mortality in tropical and subtropical countries even though existing treatment methods can prevent most deaths if presentation occurs early to hospitals. Envenomation by unidentified snakes is common in central Sri Lanka. Management of such patients is challenging especially if presentation is late. CASE PRESENTATION: Here, we report a case of a 52-year-old man from central Sri Lanka who presented late after being bitten by an unidentified snake. He developed `severe coagulopathy, neurotoxicity, acute kidney injury, and rhabdomyolysis. Subsequently, despite of treatment, he died due to extensive hemorrhaging in many organs. A large intracranial hemorrhage lead to fatal brain herniation. CONCLUSIONS: Envenomation by some snake species can severely affect multiple body systems and give rise to fatal brain hemorrhages and brain herniation. Considering the known effects of local snake venom, the responsible species is likely to be Russell’s viper (Daboia russelii). We recommend some simple measures to reduce the chances of such deaths in the future.
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spelling pubmed-50222102016-09-20 Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake Ehelepola, N. D. B. Samaranayake, S. M. A. N. Basnayake, B. M. L. S. Amiyangoda, C. G. K. Dhanapala, D. M. U. C. B. Kalupahana, K. L. R. Trop Med Health Case Report BACKGROUND: Snakebites cause considerable morbidity and mortality in tropical and subtropical countries even though existing treatment methods can prevent most deaths if presentation occurs early to hospitals. Envenomation by unidentified snakes is common in central Sri Lanka. Management of such patients is challenging especially if presentation is late. CASE PRESENTATION: Here, we report a case of a 52-year-old man from central Sri Lanka who presented late after being bitten by an unidentified snake. He developed `severe coagulopathy, neurotoxicity, acute kidney injury, and rhabdomyolysis. Subsequently, despite of treatment, he died due to extensive hemorrhaging in many organs. A large intracranial hemorrhage lead to fatal brain herniation. CONCLUSIONS: Envenomation by some snake species can severely affect multiple body systems and give rise to fatal brain hemorrhages and brain herniation. Considering the known effects of local snake venom, the responsible species is likely to be Russell’s viper (Daboia russelii). We recommend some simple measures to reduce the chances of such deaths in the future. BioMed Central 2016-09-13 /pmc/articles/PMC5022210/ /pubmed/27651731 http://dx.doi.org/10.1186/s41182-016-0029-2 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Ehelepola, N. D. B.
Samaranayake, S. M. A. N.
Basnayake, B. M. L. S.
Amiyangoda, C. G. K.
Dhanapala, D. M. U. C. B.
Kalupahana, K. L. R.
Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
title Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
title_full Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
title_fullStr Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
title_full_unstemmed Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
title_short Multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
title_sort multisystem failure and death due to extensive hemorrhaging and brain herniation subsequent to a bite by an unidentified snake
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022210/
https://www.ncbi.nlm.nih.gov/pubmed/27651731
http://dx.doi.org/10.1186/s41182-016-0029-2
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