Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy

BACKGROUND: Peripheral inflammation contributes to the neurological alterations in hepatic encephalopathy (HE). Neuroinflammation and altered GABAergic neurotransmission mediate cognitive and motor alterations in rats with HE. It remains unclear (a) if neuroinflammation and neurological impairment i...

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Detalles Bibliográficos
Autores principales: Dadsetan, Sherry, Balzano, Tiziano, Forteza, Jerónimo, Agusti, Ana, Cabrera-Pastor, Andrea, Taoro-Gonzalez, Lucas, Hernandez-Rabaza, Vicente, Gomez-Gimenez, Belen, ElMlili, Nisrin, Llansola, Marta, Felipo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022234/
https://www.ncbi.nlm.nih.gov/pubmed/27623772
http://dx.doi.org/10.1186/s12974-016-0710-8

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