Efficient Routes to a Diverse Array of Amino Alcohol-Derived Chiral Fragments

[Image: see text] Efficient syntheses of chiral fragments derived from chiral amino alcohols are described. Several unique scaffolds were readily accessed in 1–5 synthetic steps leading to 45 chiral fragments, including oxazolidinones, morpholinones, lactams, and sultams. These fragments have molecu...

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Detalles Bibliográficos
Autores principales: Haftchenary, Sina, Nelson, Shawn D., Furst, Laura, Dandapani, Sivaraman, Ferrara, Steven J., Bošković, Žarko V., Figueroa Lazú, Samuel, Guerrero, Adrian M., Serrano, Juan C., Crews, DeMarcus K., Brackeen, Cristina, Mowat, Jeffrey, Brumby, Thomas, Bauser, Marcus, Schreiber, Stuart L., Phillips, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022782/
https://www.ncbi.nlm.nih.gov/pubmed/27518324
http://dx.doi.org/10.1021/acscombsci.6b00050

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