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Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C

We have investigated the immunogenicity in rabbits of native-like, soluble, recombinant SOSIP.664 trimers based on the env genes of four isolates of human immunodeficiency virus type 1 (HIV-1); specifically BG505 (clade A), B41 (clade B), CZA97 (clade C) and DU422 (clade C). The various trimers were...

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Detalles Bibliográficos
Autores principales:	Klasse, P. J., LaBranche, Celia C., Ketas, Thomas J., Ozorowski, Gabriel, Cupo, Albert, Pugach, Pavel, Ringe, Rajesh P., Golabek, Michael, van Gils, Marit J., Guttman, Miklos, Lee, Kelly K., Wilson, Ian A., Butera, Salvatore T., Ward, Andrew B., Montefiori, David C., Sanders, Rogier W., Moore, John P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023125/ https://www.ncbi.nlm.nih.gov/pubmed/27627672 http://dx.doi.org/10.1371/journal.ppat.1005864

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