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Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial

BACKGROUND: SSG&PM over 17 days is recommended as first line treatment for visceral leishmaniasis in eastern Africa, but is painful and requires hospitalization. Combination regimens including AmBisome and miltefosine are safe and effective in India, but there are no published data from trials o...

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Detalles Bibliográficos
Autores principales: Wasunna, Monique, Njenga, Simon, Balasegaram, Manica, Alexander, Neal, Omollo, Raymond, Edwards, Tansy, Dorlo, Thomas P. C., Musa, Brima, Ali, Mohammed Hassan Sharaf, Elamin, Mohammed Yasein, Kirigi, George, Juma, Rashid, Kip, Anke E., Schoone, Gerard J., Hailu, Asrat, Olobo, Joseph, Ellis, Sally, Kimutai, Robert, Wells, Susan, Khalil, Eltahir Awad Gasim, Strub Wourgaft, Nathalie, Alves, Fabiana, Musa, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023160/
https://www.ncbi.nlm.nih.gov/pubmed/27627654
http://dx.doi.org/10.1371/journal.pntd.0004880