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Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling

Increasing evidence suggests that gut microbiota is an environmental factor that plays a crucial role in obesity. However, the aetiology of obesity is rather complex and depends on different factors. Furthermore, there is a lack of consensus about the exact role that this microbial community plays i...

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Detalles Bibliográficos
Autores principales: Aguirre, Marisol, Venema, Koen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023237/
https://www.ncbi.nlm.nih.gov/pubmed/27682087
http://dx.doi.org/10.3390/microorganisms3020213
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author Aguirre, Marisol
Venema, Koen
author_facet Aguirre, Marisol
Venema, Koen
author_sort Aguirre, Marisol
collection PubMed
description Increasing evidence suggests that gut microbiota is an environmental factor that plays a crucial role in obesity. However, the aetiology of obesity is rather complex and depends on different factors. Furthermore, there is a lack of consensus about the exact role that this microbial community plays in the host. The aim of this review is to present evidence about what has been characterized, compositionally and functionally, as obese gut microbiota. In addition, the different reasons explaining the so-far unclear role are discussed considering evidence from in vitro, animal and human studies.
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spelling pubmed-50232372016-09-28 Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling Aguirre, Marisol Venema, Koen Microorganisms Review Increasing evidence suggests that gut microbiota is an environmental factor that plays a crucial role in obesity. However, the aetiology of obesity is rather complex and depends on different factors. Furthermore, there is a lack of consensus about the exact role that this microbial community plays in the host. The aim of this review is to present evidence about what has been characterized, compositionally and functionally, as obese gut microbiota. In addition, the different reasons explaining the so-far unclear role are discussed considering evidence from in vitro, animal and human studies. MDPI 2015-04-27 /pmc/articles/PMC5023237/ /pubmed/27682087 http://dx.doi.org/10.3390/microorganisms3020213 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aguirre, Marisol
Venema, Koen
Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling
title Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling
title_full Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling
title_fullStr Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling
title_full_unstemmed Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling
title_short Does the Gut Microbiota Contribute to Obesity? Going beyond the Gut Feeling
title_sort does the gut microbiota contribute to obesity? going beyond the gut feeling
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023237/
https://www.ncbi.nlm.nih.gov/pubmed/27682087
http://dx.doi.org/10.3390/microorganisms3020213
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