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Parallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1

Bioengineering holds great promise to provide fast and efficient biocatalysts for methanol-based biotechnology, but necessitates proven methods to optimize physiology in engineered strains. Here, we highlight experimental evolution as an effective means for optimizing an engineered Methylobacterium...

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Detalles Bibliográficos
Autores principales: Carroll, Sean Michael, Chubiz, Lon M., Agashe, Deepa, Marx, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023240/
https://www.ncbi.nlm.nih.gov/pubmed/27682084
http://dx.doi.org/10.3390/microorganisms3020152

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