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Parallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1
Bioengineering holds great promise to provide fast and efficient biocatalysts for methanol-based biotechnology, but necessitates proven methods to optimize physiology in engineered strains. Here, we highlight experimental evolution as an effective means for optimizing an engineered Methylobacterium...
Autores principales: | Carroll, Sean Michael, Chubiz, Lon M., Agashe, Deepa, Marx, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023240/ https://www.ncbi.nlm.nih.gov/pubmed/27682084 http://dx.doi.org/10.3390/microorganisms3020152 |
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