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Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers

We have conducted a phase 1 study of intravenous vvDD, a Western Reserve strain oncolytic vaccinia virus, on 11 patients with standard treatment-refractory advanced colorectal or other solid cancers. The primary endpoints were maximum tolerated dose and associated toxicity while secondary endpoints...

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Detalles Bibliográficos
Autores principales:	Downs-Canner, Stephanie, Guo, Zong Sheng, Ravindranathan, Roshni, Breitbach, Caroline J, O'Malley, Mark E, Jones, Heather L, Moon, Anne, McCart, Judith Andrea, Shuai, Yongli, Zeh, Herbert J, Bartlett, David L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023393/ https://www.ncbi.nlm.nih.gov/pubmed/27203445 http://dx.doi.org/10.1038/mt.2016.101

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