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DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations
Adeno-associated viral (AAV) vectors are considered as one of the most promising delivery systems in human gene therapy. In addition, AAV vectors are frequently applied tools in preclinical and basic research. Despite this success, manufacturing pure AAV vector preparations remains a difficult task....
Autores principales: | Schnödt, Maria, Schmeer, Marco, Kracher, Barbara, Krüsemann, Christa, Espinosa, Laura Escalona, Grünert, Anja, Fuchsluger, Thomas, Rischmüller, Anja, Schleef, Martin, Büning, Hildegard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023404/ https://www.ncbi.nlm.nih.gov/pubmed/28131313 http://dx.doi.org/10.1038/mtna.2016.60 |
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