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Effects of Fibrotic Tissue on Liver-targeted Hydrodynamic Gene Delivery
Hydrodynamic gene delivery is a common method for gene transfer to the liver of small animals, and its clinical applicability in large animals has been demonstrated. Previous studies focused on functional analyses of therapeutic genes in animals with normal livers and little, however, is known regar...
Autores principales: | Kobayashi, Yuji, Kamimura, Kenya, Abe, Hiroyuki, Yokoo, Takeshi, Ogawa, Kohei, Shinagawa-Kobayashi, Yoko, Goto, Ryo, Inoue, Ryosuke, Ohtsuka, Masato, Miura, Hiromi, Kanefuji, Tsutomu, Suda, Takeshi, Tsuchida, Masanori, Aoyagi, Yutaka, Zhang, Guisheng, Liu, Dexi, Terai, Shuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023407/ https://www.ncbi.nlm.nih.gov/pubmed/27574785 http://dx.doi.org/10.1038/mtna.2016.63 |
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