Effects of Kras activation and Pten deletion alone or in combination on MUC1 biology and epithelial to mesenchymal transition in ovarian cancer

Mucin1 (MUC1) is an epithelial glycoprotein overexpressed in ovarian cancer and actively involved in tumor cell migration and metastasis. Using novel in vitro and in vivo MUC1-expressing conditional (Cre-loxP) ovarian tumor models, we focus here on MUC1 biology and the roles of Kras activation and P...

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Detalles Bibliográficos
Autores principales: Zhang, Lixin, Ma, Tianzhou, Brozick, Joan, Babalola, Kathlene, Budiu, Raluca, Tseng, George, Vlad, Anda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023457/
https://www.ncbi.nlm.nih.gov/pubmed/26973247
http://dx.doi.org/10.1038/onc.2016.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023457/
https://www.ncbi.nlm.nih.gov/pubmed/26973247
http://dx.doi.org/10.1038/onc.2016.53

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