Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review

BACKGROUND: Thalidomide has been successful use in patients with refractory Crohn disease (CD) in recent years. METHODS: We collected the data of a postoperative CD patient who was prescribed thalidomide to induce remission and reviewed the relevant literatures. RESULTS: A 51-year-old female was dia...

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Autores principales: Hu, Huiqin, Wang, Xinying, Liu, Side
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
4500
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023912/
https://www.ncbi.nlm.nih.gov/pubmed/27603389
http://dx.doi.org/10.1097/MD.0000000000004799
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author Hu, Huiqin
Wang, Xinying
Liu, Side
author_facet Hu, Huiqin
Wang, Xinying
Liu, Side
author_sort Hu, Huiqin
collection PubMed
description BACKGROUND: Thalidomide has been successful use in patients with refractory Crohn disease (CD) in recent years. METHODS: We collected the data of a postoperative CD patient who was prescribed thalidomide to induce remission and reviewed the relevant literatures. RESULTS: A 51-year-old female was diagnosed as CD after an urgent terminal intestinal resection and presented endoscopic recurrence despite the prophylactic treatment with azathioprine (AZA). Fortunately, she achieved mucosal healing (MH) at a low dose of thalidomide for 15 months. CONCLUSION: Thalidomide is effective to induce MH in the postoperative CD endoscopic recurrence.
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spelling pubmed-50239122016-09-26 Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review Hu, Huiqin Wang, Xinying Liu, Side Medicine (Baltimore) 4500 BACKGROUND: Thalidomide has been successful use in patients with refractory Crohn disease (CD) in recent years. METHODS: We collected the data of a postoperative CD patient who was prescribed thalidomide to induce remission and reviewed the relevant literatures. RESULTS: A 51-year-old female was diagnosed as CD after an urgent terminal intestinal resection and presented endoscopic recurrence despite the prophylactic treatment with azathioprine (AZA). Fortunately, she achieved mucosal healing (MH) at a low dose of thalidomide for 15 months. CONCLUSION: Thalidomide is effective to induce MH in the postoperative CD endoscopic recurrence. Wolters Kluwer Health 2016-09-09 /pmc/articles/PMC5023912/ /pubmed/27603389 http://dx.doi.org/10.1097/MD.0000000000004799 Text en Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-No Derivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0
spellingShingle 4500
Hu, Huiqin
Wang, Xinying
Liu, Side
Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review
title Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review
title_full Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review
title_fullStr Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review
title_full_unstemmed Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review
title_short Thalidomide induces mucosal healing in postoperative Crohn disease endoscopic recurrence: Case report and literature review
title_sort thalidomide induces mucosal healing in postoperative crohn disease endoscopic recurrence: case report and literature review
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023912/
https://www.ncbi.nlm.nih.gov/pubmed/27603389
http://dx.doi.org/10.1097/MD.0000000000004799
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AT liuside thalidomideinducesmucosalhealinginpostoperativecrohndiseaseendoscopicrecurrencecasereportandliteraturereview

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