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Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations

Enteropathy-associated T-cell lymphoma (EATL), a rare and aggressive intestinal malignancy of intraepithelial T lymphocytes, comprises two disease variants (EATL-I and EATL-II) differing in clinical characteristics and pathological features. Here we report findings derived from whole-exome sequencin...

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Detalles Bibliográficos
Autores principales: Roberti, Annalisa, Dobay, Maria Pamela, Bisig, Bettina, Vallois, David, Boéchat, Cloé, Lanitis, Evripidis, Bouchindhomme, Brigitte, Parrens, Marie- Cécile, Bossard, Céline, Quintanilla-Martinez, Leticia, Missiaglia, Edoardo, Gaulard, Philippe, de Leval, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023950/
https://www.ncbi.nlm.nih.gov/pubmed/27600764
http://dx.doi.org/10.1038/ncomms12602