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Pharmacokinetics and Dose Recommendations for Cyclosporine and Tacrolimus When Coadministered With ABT‐450, Ombitasvir, and Dasabuvir
The authors describe the drug–drug interaction profile of the he patitis C direct‐acting antiviral agents ABT‐450, ombitasvir, and dasabuvir with cyclosporine A and tacrolimus, and use pha rmacokinetic simulations to develop recommendations for reduced doses of cyclosporine A and tacrolimus in postt...
Autores principales: | Badri, P., Dutta, S., Coakley, E., Cohen, D., Ding, B., Podsadecki, T., Bernstein, B., Awni, W., Menon, R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024008/ https://www.ncbi.nlm.nih.gov/pubmed/25708713 http://dx.doi.org/10.1111/ajt.13111 |
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