Effervescent N-Acetylcysteine Tablets versus Oral Solution N-Acetylcysteine in Fasting Healthy Adults: An Open-Label, Randomized, Single-Dose, Crossover, Relative Bioavailability Study

BACKGROUND: Oral solution N-acetylcysteine (NAC) is an antidote for acetaminophen overdose, but its unpleasant taste and aroma can impede delivery even after the coadministration of antiemetic medications. Flavored effervescent NAC tablets dissolved in water might be a more palatable formulation tha...

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Detalles Bibliográficos
Autores principales: Greene, Spencer C., Noonan, Patrick K., Sanabria, Carlos, Peacock, W. Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024139/
https://www.ncbi.nlm.nih.gov/pubmed/27668024
http://dx.doi.org/10.1016/j.curtheres.2016.06.001

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