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Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation

Previous studies demonstrated that acute alcohol intoxication caused hepatic lipid accumulation. The present study showed that acute alcohol intoxication caused hepatic lipid accumulation in Tlr4-wild-type mice but not in Tlr4-mutant mice. Hepatic sterol-regulatory element binding protein (SREBP)-1,...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhi-Hui, Liu, Xiao-Qian, Zhang, Cheng, He, Wei, Wang, Hua, Chen, Yuan-Hua, Liu, Xiao-Jing, Chen, Xi, Xu, De-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024165/ https://www.ncbi.nlm.nih.gov/pubmed/27627966 http://dx.doi.org/10.1038/srep33513

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