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The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity

TRPM7 is a member of the Transient-Receptor-Potential Melastatin ion channel family. TRPM7 is a unique fusion protein of an ion channel and an α-kinase. Although mammalian TRPM7 is well characterized biophysically and its pivotal role in cancer, ischemia and cardiovascular disease is becoming increa...

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Detalles Bibliográficos
Autores principales: Jansen, Chad, Sahni, Jaya, Suzuki, Sayuri, Horgen, F. David, Penner, Reinhold, Fleig, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024298/
https://www.ncbi.nlm.nih.gov/pubmed/27628598
http://dx.doi.org/10.1038/srep33459