SELMAP - SELEX affinity landscape MAPping of transcription factor binding sites using integrated microfluidics

Transcription factors (TFs) alter gene expression in response to changes in the environment through sequence-specific interactions with the DNA. These interactions are best portrayed as a landscape of TF binding affinities. Current methods to study sequence-specific binding preferences suffer from l...

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Detalles Bibliográficos
Autores principales: Chen, Dana, Orenstein, Yaron, Golodnitsky, Rada, Pellach, Michal, Avrahami, Dorit, Wachtel, Chaim, Ovadia-Shochat, Avital, Shir-Shapira, Hila, Kedmi, Adi, Juven-Gershon, Tamar, Shamir, Ron, Gerber, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024299/
https://www.ncbi.nlm.nih.gov/pubmed/27628341
http://dx.doi.org/10.1038/srep33351

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