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Crystal structures of the bifunctional tRNA methyltransferase Trm5a

tRNA methyltransferase Trm5 catalyses the transfer of a methyl group from S-adenosyl-L-methionine to G37 in eukaryotes and archaea. The N1-methylated guanosine is the product of the initial step of the wyosine hypermodification, which is essential for the maintenance of the reading frame during tran...

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Detalles Bibliográficos
Autores principales:	Wang, Caiyan, Jia, Qian, Chen, Ran, Wei, Yuming, Li, Juntao, Ma, Jie, Xie, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024318/ https://www.ncbi.nlm.nih.gov/pubmed/27629654 http://dx.doi.org/10.1038/srep33553

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