Methylcrotonoyl-CoA carboxylase 1 potentiates RLR-induced NF-κB signaling by targeting MAVS complex

RNA virus infections are detected by the RIG-I family of receptors, which signal through the adaptor molecule mitochondrial antiviral signaling (MAVS). MAVS then recruits the adaptor’s tumor necrosis factor receptor-associated factor (TRAF) 3 and TRAF6, which in turn activate IRF3 and NF-κB, respect...

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Detalles Bibliográficos
Autores principales: Cao, Zhongying, Xia, Zhangchuan, Zhou, Yaqin, Yang, Xiaodan, Hao, Hua, Peng, Nanfang, Liu, Shi, Zhu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024325/
https://www.ncbi.nlm.nih.gov/pubmed/27629939
http://dx.doi.org/10.1038/srep33557

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