Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models

Mammalian sperm acquire fertilizing capacity in the female tract in a process called capacitation. At the molecular level, capacitation requires protein kinase A activation, changes in membrane potential and an increase in intracellular calcium. Inhibition of these pathways results in loss of fertil...

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Detalles Bibliográficos
Autores principales: Navarrete, Felipe A., Alvau, Antonio, Lee, Hoi Chang, Levin, Lonny R., Buck, Jochen, Leon, Patricia Martin-De, Santi, Celia M., Krapf, Dario, Mager, Jesse, Fissore, Rafael A., Salicioni, Ana M., Darszon, Alberto, Visconti, Pablo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024339/
https://www.ncbi.nlm.nih.gov/pubmed/27627854
http://dx.doi.org/10.1038/srep33589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024339/
https://www.ncbi.nlm.nih.gov/pubmed/27627854
http://dx.doi.org/10.1038/srep33589

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