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Rituximab induces phenotypical and functional changes of NK cells in a non-malignant experimental setting
BACKGROUND: Rituximab has broad and increasing application in rheumatic diseases. It is known from lymphoma studies that natural killer (NK) cells can lyse rituximab-coated transformed B cells. However, the role of NK cells in mediating rituximab-induced depletion of non-malignant B cells is unknown...
Autores principales: | Merkt, Wolfgang, Lorenz, Hanns-Martin, Watzl, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024429/ https://www.ncbi.nlm.nih.gov/pubmed/27629249 http://dx.doi.org/10.1186/s13075-016-1101-3 |
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