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Oxidative damage and chemokine production dominate days before immune cell infiltration and EAE disease debut
BACKGROUND: Multiple sclerosis is widely accepted as an inflammatory disease. However, studies indicate that degenerative processes in the CNS occur prior to inflammation. In the widely used animal model experimental autoimmune encephalomyelitis (EAE), we investigated the significance of degenerativ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024447/ https://www.ncbi.nlm.nih.gov/pubmed/27630002 http://dx.doi.org/10.1186/s12974-016-0707-3 |