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Multiplexed automated digital quantification of fusion transcripts: comparative study with fluorescent in-situ hybridization (FISH) technique in acute leukemia patients

BACKGROUND: The World Health Organization (WHO) classification system defines recurrent chromosomal translocations as the sole diagnostic and prognostic criteria for acute leukemia (AL). These fusion transcripts are pivotal in the pathogenesis of AL. Clinical laboratories universally employ conventi...

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Detalles Bibliográficos
Autores principales:	Akhter, Ariz, Mughal, Muhammad Kashif, Elyamany, Ghaleb, Sinclair, Gary, Azma, Raja Zahratul, Masir, Noraidah, Shuib, Salwati, Rashid-Kolvear, Fariborz, Shabani-Rad, Meer-Taher, Stewart, Douglas Allan, Mansoor, Adnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024455/ https://www.ncbi.nlm.nih.gov/pubmed/27632978 http://dx.doi.org/10.1186/s13000-016-0541-z

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