Using a constraint-based regression method for relative quantification of somatic mutations in pyrosequencing signals: a case for NRAS analysis

BACKGROUND: Pyrosequencing Allele Quantification (AQ) is a cost-effective DNA sequencing method that can be used for detecting somatic mutations in formalin-fixed paraffin-embedded (FFPE) samples. The method displays a low turnaround time and a high sensitivity. Pyrosequencing suffers however from t...

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Detalles Bibliográficos
Autores principales: Ambroise, Jerome, Badir, Jamal, Nienhaus, Louise, Robert, Annie, Dekairelle, Anne-France, Gala, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024468/
https://www.ncbi.nlm.nih.gov/pubmed/27651826
http://dx.doi.org/10.1186/s13015-016-0086-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024468/
https://www.ncbi.nlm.nih.gov/pubmed/27651826
http://dx.doi.org/10.1186/s13015-016-0086-4

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