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A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo

The androgen receptor plays a critical role in the progression of prostate cancer. Here, we describe targeting the prostate-specific membrane antigen using a lipid nanoparticle formulation containing small interfering RNA designed to silence expression of the messenger RNA encoding the androgen rece...

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Detalles Bibliográficos
Autores principales:	Lee, Justin B, Zhang, Kaixin, Tam, Yuen Yi C, Quick, Joslyn, Tam, Ying K, Lin, Paulo JC, Chen, Sam, Liu, Yan, Nair, Jayaprakash K, Zlatev, Ivan, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Rennie, Paul S, Cullis, Pieter R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024509/ https://www.ncbi.nlm.nih.gov/pubmed/28131285 http://dx.doi.org/10.1038/mtna.2016.43

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