Hypophosphatemia promotes lower rates of muscle ATP synthesis

Hypophosphatemia can lead to muscle weakness and respiratory and heart failure, but the mechanism is unknown. To address this question, we noninvasively assessed rates of muscle ATP synthesis in hypophosphatemic mice by using in vivo saturation transfer [(31)P]-magnetic resonance spectroscopy. By us...

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Detalles Bibliográficos
Autores principales: Pesta, Dominik H., Tsirigotis, Dimitrios N., Befroy, Douglas E., Caballero, Daniel, Jurczak, Michael J., Rahimi, Yasmeen, Cline, Gary W., Dufour, Sylvie, Birkenfeld, Andreas L., Rothman, Douglas L., Carpenter, Thomas O., Insogna, Karl, Petersen, Kitt Falk, Bergwitz, Clemens, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024687/
https://www.ncbi.nlm.nih.gov/pubmed/27338702
http://dx.doi.org/10.1096/fj.201600473R

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