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Dual randomization of oligonucleotides to reduce the bias in ribosome-profiling libraries
Protein translation is at the heart of cellular metabolism and its in-depth characterization is key for many lines of research. Recently, ribosome profiling became the state-of-the-art method to quantitatively characterize translation dynamics at a transcriptome-wide level. However, the strategy of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024760/ https://www.ncbi.nlm.nih.gov/pubmed/27450428 http://dx.doi.org/10.1016/j.ymeth.2016.07.011 |