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The Contribution of Mosaic Variants to Autism Spectrum Disorder
De novo mutation is highly implicated in autism spectrum disorder (ASD). However, the contribution of post-zygotic mutation to ASD is poorly characterized. We performed both exome sequencing of paired samples and analysis of de novo variants from whole-exome sequencing of 2,388 families. While we fi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024993/ https://www.ncbi.nlm.nih.gov/pubmed/27632392 http://dx.doi.org/10.1371/journal.pgen.1006245 |