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Dental Calculus Stimulates Interleukin-1β Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes

Dental calculus is a mineralized deposit associated with periodontitis. The bacterial components contained in dental calculus can be recognized by host immune sensors, such as Toll-like receptors (TLRs), and induce transcription of proinflammatory cytokines, such as IL-1β. Studies have shown that ce...

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Detalles Bibliográficos
Autores principales:	Montenegro Raudales, Jorge Luis, Yoshimura, Atsutoshi, SM, Ziauddin, Kaneko, Takashi, Ozaki, Yukio, Ukai, Takashi, Miyazaki, Toshihiro, Latz, Eicke, Hara, Yoshitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025015/ https://www.ncbi.nlm.nih.gov/pubmed/27632566 http://dx.doi.org/10.1371/journal.pone.0162865

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