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Development of Accelerated Coronary Atherosclerosis Model Using Low Density Lipoprotein Receptor Knock-Out Swine with Balloon Injury

BACKGROUND: Several animal models have facilitated the evaluation and pathological understanding of atherosclerosis, but a definitive animal model of coronary atherosclerosis is not available. We therefore developed low density lipoprotein receptor knockout (LDLR-KO) pigs with hypercholesterolemia,...

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Detalles Bibliográficos
Autores principales:	Ogita, Manabu, Miyauchi, Katsumi, Onishi, Akira, Tsuboi, Shuta, Wada, Hideki, Konishi, Hirokazu, Naito, Ryo, Dohi, Tomotaka, Kasai, Takatoshi, Kojima, Yuko, Schwartz, Robert S., Daida, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025170/ https://www.ncbi.nlm.nih.gov/pubmed/27631974 http://dx.doi.org/10.1371/journal.pone.0163055

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