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The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review
Background. Regarding the lack of comprehensive systematic review on the efficacy of water fluoridation and prevalence of dental fluorosis, the aim of the current research was to systematically study the prevalence of dental fluorosis at different levels of water fluoride in the world and lay emphas...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025212/ https://www.ncbi.nlm.nih.gov/pubmed/27651877 http://dx.doi.org/10.15171/joddd.2016.021 |
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author | Goodarzi, Fatemeh Mahvi, Amir Hossein Hosseini, Mostafa Nedjat, Saharnaz Nabizadeh Nodehi, Ramin Kharazifard, Mohammad Javad Parvizishad, Mina Cheraghi, Zahra |
author_facet | Goodarzi, Fatemeh Mahvi, Amir Hossein Hosseini, Mostafa Nedjat, Saharnaz Nabizadeh Nodehi, Ramin Kharazifard, Mohammad Javad Parvizishad, Mina Cheraghi, Zahra |
author_sort | Goodarzi, Fatemeh |
collection | PubMed |
description | Background. Regarding the lack of comprehensive systematic review on the efficacy of water fluoridation and prevalence of dental fluorosis, the aim of the current research was to systematically study the prevalence of dental fluorosis at different levels of water fluoride in the world and lay emphasis on the amount of fluoride in drinking water. Methods. Studies were searched in PubMed, Scopus, SID, and IranMedex, with regard to inclusion criteria. Study validity was assessed with some checklists, and analyses were performed to ascertain the prevalence of dental fluorosis among individuals categorized in age groups. Results. Investigation of the heterogeneity and analysis of the subgroups revealed that in the 6-18 year age group, when water fluoride level was less than 0.7 ppm and there was exposure to water fluoride in the first 6-8 years of life, no significant heterogeneity was detected among the studies in this subgroup. Thus, the pooled estimation of dental fluorosis prevalence in this subgroup was 12.9% (95% CI: 7.5-18.3%). Furthermore, meta-regression indicated that the exposure time to fluoride in drinking water, or exposure to fluoride in supplements, diets, air, etc as well as the quality of studies had a significant relation to the difference in the prevalence of dental fluorosis. Conclusion. The results revealed no heterogeneity in just 2 subgroups, and the results of subgroups could be pooled in them. Furthermore, the number of studies included in this review considerably decreased by considering all the detected confounding factors, whereas other similar systematic reviews mentioned at most 2 factors. |
format | Online Article Text |
id | pubmed-5025212 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-50252122016-09-20 The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review Goodarzi, Fatemeh Mahvi, Amir Hossein Hosseini, Mostafa Nedjat, Saharnaz Nabizadeh Nodehi, Ramin Kharazifard, Mohammad Javad Parvizishad, Mina Cheraghi, Zahra J Dent Res Dent Clin Dent Prospects Original Article Background. Regarding the lack of comprehensive systematic review on the efficacy of water fluoridation and prevalence of dental fluorosis, the aim of the current research was to systematically study the prevalence of dental fluorosis at different levels of water fluoride in the world and lay emphasis on the amount of fluoride in drinking water. Methods. Studies were searched in PubMed, Scopus, SID, and IranMedex, with regard to inclusion criteria. Study validity was assessed with some checklists, and analyses were performed to ascertain the prevalence of dental fluorosis among individuals categorized in age groups. Results. Investigation of the heterogeneity and analysis of the subgroups revealed that in the 6-18 year age group, when water fluoride level was less than 0.7 ppm and there was exposure to water fluoride in the first 6-8 years of life, no significant heterogeneity was detected among the studies in this subgroup. Thus, the pooled estimation of dental fluorosis prevalence in this subgroup was 12.9% (95% CI: 7.5-18.3%). Furthermore, meta-regression indicated that the exposure time to fluoride in drinking water, or exposure to fluoride in supplements, diets, air, etc as well as the quality of studies had a significant relation to the difference in the prevalence of dental fluorosis. Conclusion. The results revealed no heterogeneity in just 2 subgroups, and the results of subgroups could be pooled in them. Furthermore, the number of studies included in this review considerably decreased by considering all the detected confounding factors, whereas other similar systematic reviews mentioned at most 2 factors. Tabriz University of Medical Sciences 2016 2016-08-17 /pmc/articles/PMC5025212/ /pubmed/27651877 http://dx.doi.org/10.15171/joddd.2016.021 Text en © 2016 Goodarzi et al. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article published and distributed by Tabriz University of Medical Sciences under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Goodarzi, Fatemeh Mahvi, Amir Hossein Hosseini, Mostafa Nedjat, Saharnaz Nabizadeh Nodehi, Ramin Kharazifard, Mohammad Javad Parvizishad, Mina Cheraghi, Zahra The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review |
title | The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review |
title_full | The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review |
title_fullStr | The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review |
title_full_unstemmed | The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review |
title_short | The prevalence of dental fluorosis and exposure to fluoride in drinking water: A systematic review |
title_sort | prevalence of dental fluorosis and exposure to fluoride in drinking water: a systematic review |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025212/ https://www.ncbi.nlm.nih.gov/pubmed/27651877 http://dx.doi.org/10.15171/joddd.2016.021 |
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