Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells

REST (RE1-silencing transcription factor, also called Nrsf) is involved in the maintenance of the undifferentiated state of neuronal stem/progenitor cells in vitro by preventing precocious expression of neuronal genes. REST expression was then decreased in developing neurons to down-regulate neurona...

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Detalles Bibliográficos
Autores principales: Aoki, Hitomi, Ogino, Hajime, Tomita, Hiroyuki, Hara, Akira, Kunisada, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025245/
https://www.ncbi.nlm.nih.gov/pubmed/27631609
http://dx.doi.org/10.1371/journal.pone.0163042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025245/
https://www.ncbi.nlm.nih.gov/pubmed/27631609
http://dx.doi.org/10.1371/journal.pone.0163042

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