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Numb regulates the balance between Notch recycling and late-endosome targeting in Drosophila neural progenitor cells
The Notch signaling pathway plays essential roles in both animal development and human disease. Regulation of Notch receptor levels in membrane compartments has been shown to affect signaling in a variety of contexts. Here we used steady-state and pulse-labeling techniques to follow Notch receptors...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025272/ https://www.ncbi.nlm.nih.gov/pubmed/27466320 http://dx.doi.org/10.1091/mbc.E15-11-0751 |