Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors

BACKGROUND: Calorie restriction (CR) prevents obesity and exerts anticancer effects in many preclinical models. CR is also increasingly being used in cancer patients as a sensitizing strategy prior to chemotherapy regimens. While the beneficial effects of CR are widely accepted, the mechanisms throu...

Descripción completa

Detalles Bibliográficos
Autores principales: Lashinger, Laura M., O’Flanagan, Ciara H., Dunlap, Sarah M., Rasmussen, Audrey J., Sweeney, Shannon, Guo, Jessie Yangxiang, Lodi, Alessia, Tiziani, Stefano, White, Eileen, Hursting, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025535/
https://www.ncbi.nlm.nih.gov/pubmed/27651895
http://dx.doi.org/10.1186/s40170-016-0158-4

Ejemplares similares

Ejemplares similares