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Influence of a novel histone deacetylase inhibitor panobinostat (LBH589) on the growth of ovarian cancer

BACKGROUND: Pre-clinical studies have demonstrated that natural and synthetic histone deacetylase (HDAC) inhibitors can impede the in vitro and in vivo growth of cell lines from a variety of gynecologic and other malignancies. We investigated the anti-tumor activity of panobinostat (LBH589) both in...

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Detalles Bibliográficos
Autores principales:	Garrett, Leslie A., Growdon, Whitfield B., Rueda, Bo R., Foster, Rosemary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025559/ https://www.ncbi.nlm.nih.gov/pubmed/27633667 http://dx.doi.org/10.1186/s13048-016-0267-2

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