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Silencing of Histone Deacetylase 9 Expression in Podocytes Attenuates Kidney Injury in Diabetic Nephropathy

Podocyte dysfunction is important in the onset and development of diabetic nephropathy (DN). Histone deacetylases (HDACs) have been recently proved to play critical roles in the pathogenesis of DN. As one subtype of the class IIa HDACs, HDAC9 is capable to repress/de-repress their target genes in tu...

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Detalles Bibliográficos
Autores principales: Liu, Feng, Zong, Ming, Wen, Xiaofei, Li, Xuezhu, Wang, Jun, Wang, Yi, Jiang, Wei, Li, Xiaojun, Guo, Zhongliang, Qi, Hualin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025656/
https://www.ncbi.nlm.nih.gov/pubmed/27633396
http://dx.doi.org/10.1038/srep33676