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Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media
High-resolution imaging through turbid media is a fundamental challenge of optical sciences that has attracted a lot of attention in recent years for its wide range of potential applications. Here, we demonstrate that the resolution of imaging systems looking behind a highly scattering medium can be...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025711/ https://www.ncbi.nlm.nih.gov/pubmed/27633483 http://dx.doi.org/10.1038/srep33558 |
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author | Edrei, Eitan Scarcelli, Giuliano |
author_facet | Edrei, Eitan Scarcelli, Giuliano |
author_sort | Edrei, Eitan |
collection | PubMed |
description | High-resolution imaging through turbid media is a fundamental challenge of optical sciences that has attracted a lot of attention in recent years for its wide range of potential applications. Here, we demonstrate that the resolution of imaging systems looking behind a highly scattering medium can be improved below the diffraction-limit. To achieve this, we demonstrate a novel microscopy technique enabled by the optical memory effect that uses a deconvolution image processing and thus it does not require iterative focusing, scanning or phase retrieval procedures. We show that this newly established ability of direct imaging through turbid media provides fundamental and practical advantages such as three-dimensional refocusing and unambiguous object reconstruction. |
format | Online Article Text |
id | pubmed-5025711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-50257112016-09-22 Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media Edrei, Eitan Scarcelli, Giuliano Sci Rep Article High-resolution imaging through turbid media is a fundamental challenge of optical sciences that has attracted a lot of attention in recent years for its wide range of potential applications. Here, we demonstrate that the resolution of imaging systems looking behind a highly scattering medium can be improved below the diffraction-limit. To achieve this, we demonstrate a novel microscopy technique enabled by the optical memory effect that uses a deconvolution image processing and thus it does not require iterative focusing, scanning or phase retrieval procedures. We show that this newly established ability of direct imaging through turbid media provides fundamental and practical advantages such as three-dimensional refocusing and unambiguous object reconstruction. Nature Publishing Group 2016-09-16 /pmc/articles/PMC5025711/ /pubmed/27633483 http://dx.doi.org/10.1038/srep33558 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Edrei, Eitan Scarcelli, Giuliano Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
title | Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
title_full | Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
title_fullStr | Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
title_full_unstemmed | Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
title_short | Memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
title_sort | memory-effect based deconvolution microscopy for super-resolution imaging through scattering media |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025711/ https://www.ncbi.nlm.nih.gov/pubmed/27633483 http://dx.doi.org/10.1038/srep33558 |
work_keys_str_mv | AT edreieitan memoryeffectbaseddeconvolutionmicroscopyforsuperresolutionimagingthroughscatteringmedia AT scarcelligiuliano memoryeffectbaseddeconvolutionmicroscopyforsuperresolutionimagingthroughscatteringmedia |