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Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease

BACKGROUND: Recent studies have suggested that melatonin—a hormone produced by the pineal gland under circadian control—contributes to PD‐related sleep dysfunction. We hypothesized that degenerative changes to the neural structures controlling pineal function (especially the suprachiasmatic nuclei o...

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Detalles Bibliográficos
Autores principales: Breen, David P., Nombela, Cristina, Vuono, Romina, Jones, P. Simon, Fisher, Kate, Burn, David J., Brooks, David J., Reddy, Akhilesh B., Rowe, James B., Barker, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025727/
https://www.ncbi.nlm.nih.gov/pubmed/26971528
http://dx.doi.org/10.1002/mds.26592