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Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease
BACKGROUND: Recent studies have suggested that melatonin—a hormone produced by the pineal gland under circadian control—contributes to PD‐related sleep dysfunction. We hypothesized that degenerative changes to the neural structures controlling pineal function (especially the suprachiasmatic nuclei o...
Autores principales: | Breen, David P., Nombela, Cristina, Vuono, Romina, Jones, P. Simon, Fisher, Kate, Burn, David J., Brooks, David J., Reddy, Akhilesh B., Rowe, James B., Barker, Roger A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025727/ https://www.ncbi.nlm.nih.gov/pubmed/26971528 http://dx.doi.org/10.1002/mds.26592 |
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