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Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression

Psychotomimetic and prodepressive effect by kappa opioid receptor (KOR) activation in rodents and human is widely known. Significantly, recent clinical investigations demonstrated the salutary effects of KOR antagonists in patients with treatment resistant depression, indicating essential role of KO...

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Detalles Bibliográficos
Autores principales:	Dogra, Shalini, Kumar, Ajeet, Umrao, Deepmala, Sahasrabuddhe, Amogh A., Yadav, Prem N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025743/ https://www.ncbi.nlm.nih.gov/pubmed/27634008 http://dx.doi.org/10.1038/srep33401

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