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Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages

Automated glycan assembly (AGA) has advanced from a concept to a commercial technology that rapidly provides access to diverse oligosaccharide chains as long as 30-mers. To date, AGA was mainly employed to incorporate trans-glycosidic linkages, where C2 participating protecting groups ensure stereos...

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Detalles Bibliográficos
Autores principales: Hahm, Heung Sik, Hurevich, Mattan, Seeberger, Peter H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025749/
https://www.ncbi.nlm.nih.gov/pubmed/27580973
http://dx.doi.org/10.1038/ncomms12482