Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways

Inhibition of angiogenesis is considered as one of the desirable pathways for the treatment of tumor growth and metastasis. Herein we demonstrated that a series of pyridinyl-thiazolyl carboxamide derivatives were designed, synthesized and examined against angiogenesis through a colony formation and...

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Detalles Bibliográficos
Autores principales: Zhou, Wenbo, Tang, Wenshu, Sun, Zhenliang, Li, Yunqi, Dong, Yanmin, Pei, Haixiang, Peng, Yangrui, Wang, Jinhua, Shao, Ting, Jiang, Zhenran, Yi, Zhengfang, Chen, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025770/
https://www.ncbi.nlm.nih.gov/pubmed/27633259
http://dx.doi.org/10.1038/srep33434

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